PDGFRL antibody (AA 328-357)

Catalog No. ABIN3032250

Product Details anti-PDGFRL Antibody

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Binding Specificity: AA 328-357

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogen: A portion of amino acids 328-357 from the human protein was used as the immunogen for this PDGFRL antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PDGFRL antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PDGFRL antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PDGFRL (PDGFRL Products)

Synonyms: zgc:56104 antibody, zgc:77677 antibody, MGC82397 antibody, PDGFRL antibody, pdgrl antibody, prlts antibody, MGC107901 antibody, PDGRL antibody, PRLTS antibody, 1110039P19Rik antibody, AV013190 antibody, platelet-derived growth factor receptor-like antibody, platelet derived growth factor receptor like L homeolog antibody, platelet derived growth factor receptor like antibody, pdgfrl antibody, pdgfrl.L antibody, PDGFRL antibody, Pdgfrl antibody

Background: PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling