PCSK2 antibody (AA 87-116)
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- Target See all PCSK2 Antibodies
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
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Binding Specificity
- AA 87-116
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCSK2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- Cross-Reactivity (Details)
- Expected species reactivity: Rat, Pig
- Purification
- Purified
- Immunogen
- A portion of amino acids 87-116 from the human protein was used as the immunogen for this PCSK2 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PCSK2 Primary Antibody
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- Application Notes
- Titration of the PCSK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the PCSK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- Alternative Name
- PCSK2 (PCSK2 Products)
- Synonyms
- NEC 2 antibody, NEC-2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody, PCSK2 antibody, 6330411F23Rik antibody, AI839700 antibody, Nec-2 antibody, Nec2 antibody, Phpp-2 antibody, pc2 antibody, nec2 antibody, spc2 antibody, pcsk2 antibody, pcsk2-A antibody, proprotein convertase subtilisin/kexin type 2 antibody, proprotein convertase subtilisin/kexin type 2 L homeolog antibody, PCSK2 antibody, pcsk2 antibody, Pcsk2 antibody, pcsk2.L antibody
- Background
- PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.
- UniProt
- P16519
- Pathways
- Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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