PAK4 antibody (AA 187-216)
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- Target See all PAK4 Antibodies
- PAK4 (P21-Activated Kinase 4 (PAK4))
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Binding Specificity
- AA 187-216
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAK4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 187-216 from the mouse protein was used as the immunogen for this Pak4 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PAK4 Primary Antibody
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- Application Notes
- Titration of the Pak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the Pak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- PAK4 (P21-Activated Kinase 4 (PAK4))
- Alternative Name
- Pak4 (PAK4 Products)
- Synonyms
- 5730488L07Rik antibody, AW555722 antibody, mKIAA1142 antibody, im:5916170 antibody, wu:fd12b01 antibody, zgc:92014 antibody, p21 (RAC1) activated kinase 4 antibody, p21 protein (Cdc42/Rac)-activated kinase 4 antibody, PAK4 antibody, Pak4 antibody, pak4 antibody
- Background
- Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
- UniProt
- Q8BTW9
- Pathways
- RTK Signaling
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