NOTCH4 antibody (C-Term)
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- Target See all NOTCH4 Antibodies
- NOTCH4 (Notch 4 (NOTCH4))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NOTCH4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogen
- This NOTCH4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1819-1851 amino acids from the C-terminal region of human NOTCH4.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product NOTCH4 Primary Antibody
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- Application Notes
- Titration of the NOTCH4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the NOTCH4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- NOTCH4 (Notch 4 (NOTCH4))
- Alternative Name
- NOTCH4 (NOTCH4 Products)
- Background
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
- UniProt
- Q99466
- Pathways
- Notch Signaling
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