NLRP10 antibody (AA 466-494)

Catalog No. ABIN3032014

Product Details anti-NLRP10 Antibody

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Binding Specificity: AA 466-494

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP10 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 466-494 from the human protein was used as the immunogen for this NLRP10 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NLRP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NLRP10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Alternative Name: NLRP10 (NLRP10 Products)

Background: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].

UniProt: Q86W26

Pathways: Inflammasome