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MYB antibody (AA 506-534)

MYB Reactivity: Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029530
  • Target See all MYB Antibodies
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    Binding Specificity
    • 15
    • 12
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 506-534
    Reactivity
    • 119
    • 56
    • 9
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 100
    • 20
    • 3
    • 2
    Rabbit
    Clonality
    • 106
    • 19
    Polyclonal
    Conjugate
    • 82
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYB antibody is un-conjugated
    Application
    • 96
    • 59
    • 47
    • 24
    • 23
    • 13
    • 13
    • 11
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 506-534 from the human protein was used as the immunogen for this Myb antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MYB Primary Antibody
  • Application Notes
    Titration of the Myb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Myb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    Alternative Name
    Myb (MYB Products)
    Synonyms
    Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody
    Background
    Myb is a transcriptional activator, DNA-binding protein that recognizes the sequence 5'-YAAC[GT]G-3'. It participates in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed predominantly in haematopoietic cells and immature gastroepithelial cells. TRAF7 stimulates the sumoylation of Myb at Lys-523 and Lys-499, which are the same sites as those used for PIASy-induced sumoylation. A correlation has been established between reduction in sumoylation of Myb and increase in transcriptional activation. Negative influence on transactivation properties by the negative regulatory domain region of c-Myb depends on upon sumoylation.
    UniProt
    P10242
    Pathways
    Chromatin Binding, Positive Regulation of Immune Effector Process
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