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MUSK antibody

MUSK Reactivity: Human, Mouse WB, ELISA, FACS, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031879
  • Target See all MUSK Antibodies
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    Reactivity
    • 72
    • 28
    • 25
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 66
    • 8
    • 2
    Rabbit
    Clonality
    • 71
    • 8
    Polyclonal
    Conjugate
    • 39
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUSK antibody is un-conjugated
    Application
    • 66
    • 34
    • 30
    • 13
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
    Purification
    Purified
    Immunogen
    This MUSK antibody was produced from rabbits immunized with human MUSK recombinant protein.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MUSK Primary Antibody
  • Application Notes
    Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the MUSK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    Alternative Name
    MUSK (MUSK Products)
    Synonyms
    unp antibody, fj98e12 antibody, zgc:63467 antibody, wu:fj98e12 antibody, si:dz46m7.2 antibody, si:dz57f23.3 antibody, si:busm1-57f23.3 antibody, musk-A antibody, MuSK antibody, MUSK antibody, Mdk4 antibody, Mlk antibody, Nsk1 antibody, Nsk2 antibody, Nsk3 antibody, muscle antibody, muscle associated receptor tyrosine kinase antibody, muscle, skeletal, receptor tyrosine kinase antibody, muscle associated receptor tyrosine kinase S homeolog antibody, MUSK antibody, musk antibody, musk.S antibody, Musk antibody
    Background
    MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
    UniProt
    O15146
    Pathways
    RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
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