STK4 antibody (AA 385-415)

Catalog No. ABIN3032542

Product Details anti-STK4 Antibody

Target: STK4 (serine/threonine Kinase 4 (STK4))

Binding Specificity: AA 385-415

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Purified

Immunogen: A portion of amino acids 385-415 from the human protein was used as the immunogen for this MST1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MST1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MST1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Alternative Name: MST1 (Mammalian STE20-Like Protein Kinase 1) (STK4 Products)

Synonyms: KRS2 antibody, MST1 antibody, TIIAC antibody, YSK3 antibody, AI447339 antibody, AU020804 antibody, Kas-2 antibody, Mst1 antibody, Ysk3 antibody, krs2 antibody, mst1 antibody, ysk3 antibody, serine/threonine kinase 4 antibody, serine/threonine kinase 4 S homeolog antibody, STK4 antibody, Stk4 antibody, stk4.S antibody

Background: MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.

UniProt: Q13043

Pathways: Tube Formation