LRP6 antibody (AA 1531-1560)
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- Target See all LRP6 Antibodies
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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Binding Specificity
- AA 1531-1560
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LRP6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- Purified
- Immunogen
- A portion of amino acids 1531-1560 from the human protein was used as the immunogen for this LRP6 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product LRP6 Primary Antibody
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anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1198-1370) antibody
LRP6 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 1A3F5 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (C-Term) antibodyLRP6 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1531-1560), (C-Term) antibodyLRP6 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB01837 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1546-1560) antibodyVerified LRP6 Reactivity: Human IHC, ELISA, FACS Host: Goat Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 981-1213) antibodyLRP6 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-150) antibodyLRP6 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (pSer1490) antibodyLRP6 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 981-1213) antibodyLRP6 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C3 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-150) antibodyLRP6 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (C-Term) antibodyLRP6 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the LRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the LRP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
- Alternative Name
- LRP6 (LRP6 Products)
- Synonyms
- lrp6-A antibody, Xlrp6 antibody, adcad2 antibody, lrp6 antibody, LRP6 antibody, ADCAD2 antibody, C030016K15Rik antibody, Cd antibody, Gw antibody, LDL receptor related protein 6 antibody, LDL receptor related protein 6 L homeolog antibody, LDL receptor related protein 6 S homeolog antibody, low density lipoprotein receptor-related protein 6 antibody, low-density lipoprotein receptor-related protein 6 antibody, LRP6 antibody, lrp6.L antibody, lrp6.S antibody, lrp6 antibody, Lrp6 antibody, LOC590395 antibody
- Background
- LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.
- UniProt
- O75581
- Pathways
- WNT Signaling, Tube Formation
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