K-RAS antibody (AA 146-174)

Catalog No. ABIN3031120

Product Details anti-K-RAS Antibody

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Binding Specificity: AA 146-174

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This K-RAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 146-174 from the human protein was used as the immunogen for this KRAS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the KRAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-2000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the KRAS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Alternative Name: KRAS (KRAS Products)

Synonyms: wu:fa04e08 antibody, wu:fc14b12 antibody, wu:fc23g10 antibody, wu:fj89d12 antibody, zgc:85725 antibody, Kras2 antibody, c-Ki-ras antibody, p21 antibody, C-K-RAS antibody, CFC2 antibody, K-RAS2A antibody, K-RAS2B antibody, K-RAS4A antibody, K-RAS4B antibody, KI-RAS antibody, KRAS1 antibody, KRAS2 antibody, NS antibody, NS3 antibody, RASK2 antibody, AI929937 antibody, K-ras antibody, Ki-ras antibody, Kras-2 antibody, p21B antibody, ras antibody, k-ras antibody, kras antibody, kras-a antibody, kras-b antibody, rask2 antibody, K-RAS antibody, p21ras antibody, KRAS proto-oncogene, GTPase antibody, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog antibody, Kirsten rat sarcoma viral oncogene homolog antibody, semicolonial-7 antibody, Ras family protein antibody, GTPase KRas antibody, Kirsten rat sarcoma viral oncogene homolog S homeolog antibody, KRAS antibody, kras antibody, Kras antibody, smco-7 antibody, PGTG_03066 antibody, Tsp_02666 antibody, Tsp_01642 antibody, rask antibody, kras.S antibody

Target Type: Viral Protein

Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

UniProt: P01116