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JMJD2D antibody (AA 484-516)

KDM4D Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031654
  • Target See all JMJD2D (KDM4D) Antibodies
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Binding Specificity
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 484-516
    Reactivity
    • 33
    • 3
    • 2
    • 1
    Human
    Host
    • 33
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JMJD2D antibody is un-conjugated
    Application
    • 22
    • 17
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    A portion of amino acids 484-516 from the human protein was used as the immunogen for this JMJD2D antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KDM4D Primary Antibody
  • Application Notes
    Titration of the JMJD2D antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the JMJD2D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    Alternative Name
    JMJD2D (KDM4D) (KDM4D Products)
    Synonyms
    JMJD2D antibody, 4932416A15 antibody, Jmjd2d antibody, KDM4D antibody, lysine demethylase 4D antibody, lysine-specific demethylase 4D antibody, lysine (K)-specific demethylase 4D antibody, KDM4D antibody, LOC524768 antibody, Kdm4d antibody, LOC617971 antibody, LOC100067461 antibody, LOC698455 antibody, LOC100514356 antibody
    Background
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    UniProt
    Q6B0I6
    Pathways
    Warburg Effect
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