JAK2 antibody (AA 1101-1132)
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- Target See all JAK2 Antibodies
- JAK2 (Janus Kinase 2 (JAK2))
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Binding Specificity
- AA 1101-1132
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This JAK2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
- Purification
- Purified
- Immunogen
- A portion of amino acids 1101-1132 from the human protein was used as the immunogen for this JAK2 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product JAK2 Primary Antibody
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- Application Notes
- Titration of the JAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the JAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- JAK2 (Janus Kinase 2 (JAK2))
- Alternative Name
- JAK2 (JAK2 Products)
- Background
- This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
- UniProt
- O60674
- Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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