Integrin alpha 1 antibody (AA 727-755)

Catalog No. ABIN3031359

Product Details anti-Integrin alpha 1 Antibody

Target: Integrin alpha 1 (ITGA1)

Binding Specificity: AA 727-755

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin alpha 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 727-755 from the human protein was used as the immunogen for this Integrin alpha 1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Integrin alpha 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Integrin alpha 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: Integrin alpha 1 (ITGA1 Products)

Synonyms: CD49A antibody, E130012M19Rik antibody, Vla1 antibody, CD49a antibody, VLA1 antibody, integrin alpha 1 antibody, integrin subunit alpha 1 antibody, Itga1 antibody, ITGA1 antibody

Background: ITGA1 is the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex