IL-13 antibody (AA 118-146)
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- Target See all IL-13 (IL13) Antibodies
- IL-13 (IL13) (Interleukin 13 (IL13))
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Binding Specificity
- AA 118-146
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL-13 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 118-146 from the human protein was used as the immunogen for this IL-13 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IL13 Primary Antibody
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- Application Notes
- Titration of the IL-13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the IL-13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- IL-13 (IL13) (Interleukin 13 (IL13))
- Alternative Name
- IL-13 (IL13 Products)
- Synonyms
- IL13 antibody, IL-13 antibody, P600 antibody, Il-13 antibody, L13 antibody, interleukin 13 antibody, IL13 antibody, Il13 antibody
- Background
- This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].
- UniProt
- P35225
- Pathways
- JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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