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IDH1 antibody (AA 116-143)

IDH1 Reactivity: Human, Mouse WB, IHC, ELISA, FACS, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031506
  • Target See all IDH1 Antibodies
    IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
    Binding Specificity
    • 15
    • 12
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-143
    Reactivity
    • 98
    • 57
    • 41
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 78
    • 36
    • 3
    • 1
    Rabbit
    Clonality
    • 78
    • 40
    Polyclonal
    Conjugate
    • 63
    • 10
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IDH1 antibody is un-conjugated
    Application
    • 84
    • 33
    • 30
    • 27
    • 20
    • 17
    • 15
    • 13
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Expected species reactivity: Rat, Bovine
    Purification
    Purified
    Immunogen
    A portion of amino acids 116-143 from the human protein was used as the immunogen for this IDH1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IDH1 Primary Antibody
  • Application Notes
    Titration of the IDH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the IDH1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
    Alternative Name
    IDH1 (IDH1 Products)
    Background
    IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent Isocitrate Dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [Wiki]
    UniProt
    O75874
    Pathways
    Warburg Effect
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