Histone H3.3 antibody (AA 1-30)

Catalog No. ABIN3031134

Product Details anti-Histone H3.3 Antibody

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Binding Specificity: AA 1-30

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H3.3 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from human H3F3A was used as the immunogen for this Histone H3.3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Histone H3.3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Histone H3.3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Histone H3.3

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Alternative Name: Histone H3.3 (H3F3A) (H3F3A Products)

Synonyms: H3.3A antibody, H3F3 antibody, h3f3a antibody, MGC52829 antibody, wu:fb58e10 antibody, zgc:56193 antibody, zgc:86731 antibody, H3-I antibody, H3-II antibody, H3-III antibody, H3-IV antibody, H3-V antibody, H3-VI antibody, H3-VII antibody, H3-VIII antibody, H3F3A antibody, h3.3 antibody, h3.3a antibody, CG5825 antibody, Dmel\\CG5825 antibody, H3.3 antibody, His-3.3A antibody, His3.3 antibody, PH3 antibody, dH3.3A antibody, H3 histone family member 3A antibody, H3 histone, family 3A antibody, H3 histone, family 3A L homeolog antibody, H3 histone, family 3C antibody, histone H3.3 antibody, histone cluster 1, H3a antibody, Histone H3.3A antibody, H3F3A antibody, h3f3a.L antibody, h3f3a antibody, H3F3C antibody, LOC475916 antibody, LOC480110 antibody, HIST1H3A antibody, LOAG_05159 antibody, His3.3A antibody, H3f3a antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

UniProt: P84243