G3BP1
Reactivity: Human, Mouse, Rat, Dog, Horse, Monkey, Cow, Bat
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Titration of the G3BP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the G3BP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
G3BP1
(GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
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Background
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.