Fission 1 antibody (N-Term)

Catalog No. ABIN3030967

Product Details anti-Fission 1 Antibody

Target: Fission 1 (FIS1)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: This FIS1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 6-40 amino acids from the N-terminal region of human FIS1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the FIS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FIS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: FIS1 (FIS1 Products)

Synonyms: TTC11 antibody, 2010003O14Rik antibody, Ttc11 antibody, fission, mitochondrial 1 antibody, FIS1 antibody, Fis1 antibody

Background: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity