Fatty Acid Synthase antibody (AA 942-973)

Catalog No. ABIN3030916

Product Details anti-Fatty Acid Synthase Antibody

Target: Fatty Acid Synthase (FASN)

Binding Specificity: AA 942-973

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Purified

Immunogen: A portion of amino acids 942-973 from human Fatty acid synthase was used as the immunogen for this FASN antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the FASN antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:200,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FASN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN (FASN Products)

Synonyms: FAS antibody, OA-519 antibody, SDR27X1 antibody, FASN antibody, fj34h12 antibody, wu:fj34h12 antibody, Cgl0836 antibody, A630082H08Rik antibody, BcDNA:GH07626 antibody, BcDNA:gh07626 antibody, DM_7295848 antibody, Dmel\\CG3523 antibody, Fatty acid synthase antibody, anon-EST:Posey235 antibody, anon-EST:Posey43 antibody, anon-WO0138581.1 antibody, dFAS antibody, fas antibody, fatty acid synthase antibody, fatty acid synthase Fas antibody, type I polyketide synthase antibody, Fatty acid synthase Fas antibody, Fatty Acid SyNthase antibody, fatty-acid synthase antibody, fatty-acid synthase II antibody, fatty-acid synthase fas antibody, Fatty acid synthase 1 antibody, FASN antibody, fas antibody, Fasn antibody, BAD_RS01360 antibody, fasn antibody, fasn-1 antibody, NCgl0802 antibody, fasB antibody, MT2600 antibody, TBMG_01448 antibody, FASN1 antibody

Background: FASN (Fatty acid synthase) is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

UniProt: P49327

Pathways: AMPK Signaling