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E2F1 antibody (AA 342-371)

E2F1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030786
  • Target See all E2F1 Antibodies
    E2F1 (E2F Transcription Factor 1 (E2F1))
    Binding Specificity
    • 25
    • 24
    • 19
    • 15
    • 15
    • 10
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 342-371
    Reactivity
    • 194
    • 97
    • 52
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 197
    • 12
    • 2
    Rabbit
    Clonality
    • 187
    • 24
    Polyclonal
    Conjugate
    • 91
    • 15
    • 14
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This E2F1 antibody is un-conjugated
    Application
    • 176
    • 87
    • 67
    • 66
    • 47
    • 29
    • 21
    • 19
    • 17
    • 16
    • 14
    • 13
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 342-371 from the human protein was used as the immunogen for this E2F1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product E2F1 Primary Antibody
  • Application Notes
    Titration of the E2F1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the E2F1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    E2F1 (E2F Transcription Factor 1 (E2F1))
    Alternative Name
    E2F1 (E2F1 Products)
    Background
    E2F1 is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters. [UniProt]
    UniProt
    Q01094
    Pathways
    p53 Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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