DUSP13 antibody (AA 147-173)

Catalog No. ABIN3030774

Product Details anti-DUSP13 Antibody

Target: DUSP13 (Dual Specificity Phosphatase 13 (DUSP13))

Binding Specificity: AA 147-173

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP13 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 147-173 from the human protein was used as the immunogen for this DUSP13 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the DUSP13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the DUSP13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for DUSP13

Target: DUSP13 (Dual Specificity Phosphatase 13 (DUSP13))

Alternative Name: DUSP13 (DUSP13 Products)

Synonyms: DUSP13 antibody, BEDP antibody, DUSP13A antibody, DUSP13B antibody, MDSP antibody, SKRP4 antibody, TMDP antibody, Gm1203 antibody, LMW-DSP6 antibody, TS-DSP6 antibody, dual specificity phosphatase 13 antibody, dual specificity phosphatase 13a antibody, dual specificity protein phosphatase 13 antibody, DUSP13 antibody, dusp13a antibody, CC1G_08292 antibody, Dusp13 antibody

Background: Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined.

UniProt: Q6B8I1