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RCAN1 antibody (AA 222-252)

RCAN1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032453
  • Target See all RCAN1 Antibodies
    RCAN1 (Regulator of Calcineurin 1 (RCAN1))
    Binding Specificity
    • 15
    • 11
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 222-252
    Reactivity
    • 78
    • 20
    • 18
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 73
    • 5
    • 1
    Rabbit
    Clonality
    • 77
    • 2
    Polyclonal
    Conjugate
    • 38
    • 7
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RCAN1 antibody is un-conjugated
    Application
    • 62
    • 37
    • 13
    • 13
    • 9
    • 8
    • 7
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA
    Cross-Reactivity (Details)
    Expected species reactivity: Mouse, Rat, Bovine, Hamster
    Purification
    Purified
    Immunogen
    A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RCAN1 Primary Antibody
  • Application Notes
    Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    RCAN1 (Regulator of Calcineurin 1 (RCAN1))
    Alternative Name
    DSCR1 (RCAN1 Products)
    Synonyms
    ADAPT78 antibody, CSP1 antibody, DSC1 antibody, DSCR1 antibody, MCIP1 antibody, RCN1 antibody, RCAN1 antibody, 2410048A02Rik antibody, AA408855 antibody, AI429645 antibody, AL024459 antibody, AV028423 antibody, Adapt78 antibody, CALP1L antibody, Dscr1 antibody, Mcip1 antibody, dscr1 antibody, rcan1 antibody, wu:fr92c05 antibody, adapt78 antibody, csp1 antibody, dsc1 antibody, mcip1 antibody, MGC53636 antibody, rcn1 antibody, MGC69428 antibody, regulator of calcineurin 1 antibody, regulator of calcineurin 1b antibody, regulator of calcineurin 1 L homeolog antibody, Down syndrome critical region gene 1 antibody, RCAN1 antibody, Rcan1 antibody, rcan1b antibody, rcan1.L antibody, dscr1 antibody, rcan1 antibody
    Background
    DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
    UniProt
    P53805
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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