CUX1 antibody (AA 1347-1374)

Catalog No. ABIN3030580

Product Details anti-CUX1 Antibody

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Binding Specificity: AA 1347-1374

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1347-1374 from the human protein was used as the immunogen for this CUX1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CUX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CUX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CUX1

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Alternative Name: CUX1 (CUX1 Products)

Background: CUX1 likely has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). [UniProt]

UniProt: P39880

Pathways: Cellular Glucan Metabolic Process