CFP antibody (AA 197-223)

Catalog No. ABIN3030563

Product Details anti-CFP Antibody

Target: CFP (Complement Factor P (CFP))

Binding Specificity: AA 197-223

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CFP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CFP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CFP

Target: CFP (Complement Factor P (CFP))

Alternative Name: CFP (CFP Products)

Synonyms: BFD antibody, PFC antibody, PFD antibody, PROPERDIN antibody, BCFG antibody, Pfc antibody, Properdin antibody, complement factor properdin antibody, CFP antibody, Cfp antibody

Background: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.

UniProt: P27918

Pathways: Complement System