CEBPA antibody (AA 304-330)

Catalog No. ABIN3030343

Product Details anti-CEBPA Antibody

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Binding Specificity: AA 304-330

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Cross-Reactivity (Details): Expected species reactivity: Rat, Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 304-330 from the human protein was used as the immunogen for this CEBPA antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CEBPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CEBPA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Alternative Name: CEBPA (CEBPA Products)

Synonyms: C/EBP-alpha antibody, CEBP antibody, C/ebpalpha antibody, CBF-A antibody, Cebp antibody, DBPCEP antibody, c/ebpa antibody, cb1062 antibody, wu:fj20f03 antibody, C/EBP antibody, C/EBPalpha antibody, xC/EBP antibody, cC/EBP antibody, C/EBP alpha antibody, CCAAT/enhancer binding protein alpha antibody, CCAAT/enhancer binding protein (C/EBP), alpha antibody, CCAAT/enhancer binding protein alpha L homeolog antibody, CEBPA antibody, Cebpa antibody, cebpa antibody, cebpa.L antibody

Background: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation