CDK4 antibody (AA 273-305)
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- Target See all CDK4 Antibodies
- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
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Binding Specificity
- AA 273-305
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Purified
- Immunogen
- A portion of amino acids 273-305 from the human protein was used as the immunogen for this CDK4 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CDK4 Primary Antibody
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anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 273-305), (C-Term) antibody
CDK4 Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB03154 unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) antibodyKO Validated CDK4 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 211-303) antibodyCDK4 Reactivity: Human WB, ELISA, IF, RNAi Host: Mouse Monoclonal 4F11 unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 6-295) antibodyCDK4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 272-303), (C-Term) antibodyCDK4 Reactivity: Rat WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 201-303) antibodyCDK4 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 241-303) antibodyCDK4 Reactivity: Human, Mouse, Rat, Sheep WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 272-303) antibodyCDK4 Reactivity: Human, Rat ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (C-Term) antibodyCDK4 Reactivity: Human, Rat, Sheep, Pig, Dog, Cow, Rabbit, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) antibodyCDK4 Reactivity: Human WB, ELISA, IP Host: Rabbit Monoclonal 8F2 unconjugated Recombinant Antibody
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- Application Notes
- Titration of the CDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the CDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
- Alternative Name
- CDK4 (CDK4 Products)
- Background
- CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of the gene have been reported.
- UniProt
- P11802
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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