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CDC6 antibody (AA 32-61)
CDC6
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDC6 Antibody
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Target
See all CDC6 Antibodies
CDC6
(Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
Binding Specificity
All epitopes for CDC6 antibodies
AA 32-61
Reactivity
All reactivities for CDC6 antibodies
Human
Host
All hosts for CDC6 antibodies
Rabbit
Clonality
All clonalities for CDC6 antibodies
Polyclonal
Conjugate
All conjugates for CDC6 antibodies
This CDC6 antibody is un-conjugated
Application
All applications for CDC6 antibodies
Western Blotting (WB), ELISA
Purification
Antigen affinity purified
Immunogen
A portion of amino acids 32-61 from the human protein was used as the immunogen for this CDC6 antibody.
Isotype
Ig Fraction
Top Product
Discover our top product CDC6 Primary Antibody
Alternatives
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Application Details
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Application Notes
Titration of the CDC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the CDC6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for CDC6
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Target
CDC6
(Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
Alternative Name
CDC6 (CDC6 Products )
Synonyms
CDC18L antibody, HsCDC18 antibody, HsCDC6 antibody, cell division cycle 6 antibody, CDC6 antibody, Cdc6 antibody
Background
Human CDC6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
UniProt
Q99741
Pathways
DNA Replication , Synthesis of DNA
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