CD8 alpha antibody (AA 150-180)
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- Target See all CD8 alpha (CD8A) Antibodies
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Binding Specificity
- AA 150-180
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD8 alpha antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 150-180 from the human protein was used as the immunogen for this CD8 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CD8A Primary Antibody
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- Application Notes
- Titration of the CD8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the CD8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Alternative Name
- CD8A (CD8A Products)
- Background
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional co-receptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
- UniProt
- P01732
- Pathways
- TCR Signaling
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