CD1e antibody (AA 184-212)

Catalog No. ABIN3030538

Product Details anti-CD1e Antibody

Target: CD1e

Binding Specificity: AA 184-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1e antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 184-212 from the human protein was used as the immunogen for this CD1e antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CD1e antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD1e antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD1e

Target: CD1e

Alternative Name: CD1e (CD1e Products)

Synonyms: CD1A antibody, R2 antibody, CD1-e antibody, CD1e molecule antibody, CD1E antibody, Cd1e antibody

Background: CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.

UniProt: P15812