CD1c antibody (AA 226-253)

Catalog No. ABIN3030368

Product Details anti-CD1c Antibody

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Binding Specificity: AA 226-253

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1c antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 226-253 from the human protein was used as the immunogen for this CD1c antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CD1c antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD1c antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1c (CD1C Products)

Synonyms: BDCA1 antibody, CD1 antibody, CD1A antibody, R7 antibody, CD1c molecule antibody, CD1C antibody

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

UniProt: P29017