CD11b antibody (AA 253-282)
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Binding Specificity
- AA 253-282
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD11b antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 253-282 from the human protein was used as the immunogen for this CD11b antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ITGAM Primary Antibody
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anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 145-340) antibodyITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE
anti-Integrin alpha M (ITGAM) (AA 623-728) antibodyITGAM Reactivity: Human ELISA, ICC Host: Mouse Monoclonal 3A10H5 unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3338 unconjugated
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- Application Notes
- Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the CD11b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- CD11b (ITGAM Products)
- Synonyms
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- Background
- CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
- UniProt
- P11215
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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