CCR10 antibody (AA 1-30)

Catalog No. ABIN3030489

Product Details anti-CCR10 Antibody

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Binding Specificity: AA 1-30

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR10 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR10 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CCR10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CCR10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CCR10

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Alternative Name: CCR10 (CCR10 Products)

Synonyms: GPR2 antibody, Cmkbr9 antibody, Gpr2 antibody, zgc:91924 antibody, CCR10 antibody, C-C motif chemokine receptor 10 antibody, chemokine (C-C motif) receptor 10 antibody, CCR10 antibody, Ccr10 antibody, ccr10 antibody

Background: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27, MIM 604833), CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).

UniProt: P46092