CNR2 antibody (AA 329-356)

Catalog No. ABIN3030275

Product Details anti-CNR2 Antibody

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Binding Specificity: AA 329-356

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 329-356 from the human protein was used as the immunogen for this CB2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CNR2

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Alternative Name: CB2 (CNR2 Products)

Synonyms: CNR2 antibody, CB2 antibody, cb2a antibody, cb2b antibody, CB-2 antibody, CX5 antibody, CB2C antibody, CNR2C antibody, CB2-R antibody, cannabinoid receptor 2 antibody, cannabinoid receptor 2 (macrophage) antibody, CNR2 antibody, cnr2 antibody, Cnr2 antibody

Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. Cannabinoid receptor 2 and cannabinoid receptor 1 (brain) (CNR1) have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

UniProt: P34972