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Caspase 10 antibody (AA 164-192)
CASP10
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Caspase 10 Antibody
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Target
See all Caspase 10 (CASP10) Antibodies
Caspase 10 (CASP10)
(Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
Binding Specificity
All epitopes for Caspase 10 antibodies
AA 164-192
Reactivity
All reactivities for Caspase 10 antibodies
Human
Host
All hosts for Caspase 10 antibodies
Rabbit
Clonality
All clonalities for Caspase 10 antibodies
Polyclonal
Conjugate
All conjugates for Caspase 10 antibodies
This Caspase 10 antibody is un-conjugated
Application
All applications for Caspase 10 antibodies
Western Blotting (WB), ELISA
Purification
Purified
Immunogen
A portion of amino acids 164-192 from the human protein was used as the immunogen for this Caspase-10 antibody.
Isotype
Ig Fraction
Top Product
Discover our top product CASP10 Primary Antibody
Alternatives
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Application Details
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Application Notes
Titration of the Caspase-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the Caspase-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for Caspase 10
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Target
Caspase 10 (CASP10)
(Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
Alternative Name
Caspase-10 (CASP10 Products )
Synonyms
xCaspase-10 antibody, alps2 antibody, caspace-10 antibody, caspase-10 antibody, flice2 antibody, mch4 antibody, xCaspace-10 antibody, ALPS2 antibody, FLICE2 antibody, MCH4 antibody, caspase 10 S homeolog antibody, caspase 10 antibody, caspase-10 antibody, casp10.S antibody, casp10 antibody, CASP10 antibody, Casp10 antibody, LOC100848685 antibody
Background
CASP10 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
UniProt
Q92851
Pathways
Apoptosis , Caspase Cascade in Apoptosis
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