BMP1 antibody (AA 957-986)

Catalog No. ABIN3030175

Product Details anti-BMP1 Antibody

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Binding Specificity: AA 957-986

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Purified

Immunogen: A portion of amino acids 957-986 from the human protein was used as the immunogen for this BMP1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the BMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the BMP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for BMP1

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Alternative Name: BMP1 (BMP1 Products)

Background: The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.

UniProt: P13497

Pathways: Lipid Metabolism