BIM antibody (AA 130-165)
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- Target See all BIM (BCL2L11) Antibodies
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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Binding Specificity
- AA 130-165
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BIM antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- Purified
- Immunogen
- A portion of amino acids 130-165 from the human protein was used as the immunogen for this Bim antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product BCL2L11 Primary Antibody
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anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 2-120) antibody
BCL2L11 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160) antibodyBCL2L11 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB22105 unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198) antibodyBCL2L11 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer87) antibodyBCL2L11 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 130-165) antibodyBCL2L11 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB00963 unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibodyBCL2L11 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (Middle Region) antibodyBCL2L11 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 51-150) antibodyBCL2L11 Reactivity: Human, Mouse WB, ELISA, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer69) antibodyBCL2L11 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibodyBCL2L11 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the Bim antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the Bim antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Alternative Name
- Bim (BCL2L11 Products)
- Background
- Bim belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bim contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection.
- UniProt
- O43521
- Pathways
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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