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BACE2 antibody (AA 336-365)

BACE2 Reactivity: Human WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030160
  • Target See all BACE2 Antibodies
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 336-365
    Reactivity
    • 43
    • 33
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 62
    • 2
    • 1
    Rabbit
    Clonality
    • 64
    • 1
    Polyclonal
    Conjugate
    • 29
    • 10
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BACE2 antibody is un-conjugated
    Application
    • 46
    • 30
    • 20
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    Purified
    Immunogen
    A portion of amino acids 336-365 from the human protein was used as the immunogen for this BACE2 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BACE2 Primary Antibody
  • Application Notes
    Titration of the BACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the BACE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Alternative Name
    BACE2 (BACE2 Products)
    Synonyms
    AEPLC antibody, ALP56 antibody, ASP1 antibody, ASP21 antibody, BAE2 antibody, CEAP1 antibody, DRAP antibody, 1110059C24Rik antibody, AI850424 antibody, ARP1 antibody, CDA13 antibody, beta-site APP-cleaving enzyme 2 antibody, BACE2 antibody, Bace2 antibody
    Background
    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
    UniProt
    Q9Y5Z0
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