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ATG12 antibody (AA 1-50)

ATG12 Reactivity: Human, Mouse WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030084
  • Target See all ATG12 Antibodies
    ATG12 (Autophagy Related 12 (ATG12))
    Binding Specificity
    • 15
    • 13
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50
    Reactivity
    • 78
    • 35
    • 26
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 75
    • 19
    • 2
    Rabbit
    Clonality
    • 73
    • 23
    Polyclonal
    Conjugate
    • 48
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG12 antibody is un-conjugated
    Application
    • 73
    • 40
    • 29
    • 28
    • 21
    • 13
    • 13
    • 10
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 1-50 from the human protein was used as the immunogen for this ATG12 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG12 Primary Antibody
  • Application Notes
    Titration of the ATG12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the ATG12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    ATG12 (Autophagy Related 12 (ATG12))
    Alternative Name
    ATG12 (ATG12 Products)
    Background
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

    APG12L/ATG12 is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.

    UniProt
    O94817
    Pathways
    Autophagy
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