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ASCL1 antibody (AA 63-90)

ASCL1 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029829
  • Target See all ASCL1 Antibodies
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Binding Specificity
    • 15
    • 15
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 63-90
    Reactivity
    • 83
    • 49
    • 32
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 83
    • 5
    • 3
    Rabbit
    Clonality
    • 86
    • 5
    Polyclonal
    Conjugate
    • 38
    • 10
    • 8
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCL1 antibody is un-conjugated
    Application
    • 73
    • 53
    • 23
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 63-90 from the human protein was used as the immunogen for this MASH1 / ASCL1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ASCL1 Primary Antibody
  • Application Notes
    Titration of the ASCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the ASCL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Alternative Name
    ASCL1 (MASH1) (ASCL1 Products)
    Synonyms
    ASH1 antibody, HASH1 antibody, MASH1 antibody, bHLHa46 antibody, AI225900 antibody, Mash1 antibody, ASCL1 antibody, Zash-1a antibody, ash antibody, asha antibody, id:ibd5085 antibody, im:7138587 antibody, si:dkey-264k15.2 antibody, zash1a antibody, zasha antibody, Xash1 antibody, ascl1-A antibody, Zash-1b antibody, ashb antibody, zashb antibody, achaete-scute family bHLH transcription factor 1 antibody, achaete-scute family bHLH transcription factor 1a antibody, achaete-scute family bHLH transcription factor 1 L homeolog antibody, achaete-scute complex homolog 1 antibody, achaete-scute family bHLH transcription factor 1b antibody, ASCL1 antibody, Ascl1 antibody, ascl1a antibody, ascl1.L antibody, LOC100220505 antibody, ascl1b antibody
    Background
    This gene encodes 'Achaete scute complex homolog like 1' (ASCL1) or 'Mammalian achaete scute complex homolog 1' (MASH1), a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
    UniProt
    P50553
    Pathways
    Dopaminergic Neurogenesis
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