TLR7 antibody (AA 98-128)

Catalog No. ABIN3029179

Product Details anti-TLR7 Antibody

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Binding Specificity: AA 98-128

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogen: A portion of amino acids 98-128 from the human protein was used as the immunogen for this anti-TLR7 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the anti-TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the anti-TLR7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7 (TLR7 Products)

Synonyms: TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody

Background: Toll like receptor 7 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). [UniProt]

UniProt: Q9NYK1

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades