Caspase 3 antibody (AA 60-90)
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- Target See all Caspase 3 (CASP3) Antibodies
- Caspase 3 (CASP3)
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Binding Specificity
- AA 60-90
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Purification
- Purified
- Immunogen
- A portion of amino acids 60-90 from the human protein was used as the immunogen for this anti-Caspase-3 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CASP3 Primary Antibody
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anti-Caspase 3 (CASP3) (AA 60-100) antibody
CASP3 Reactivity: Human, Mouse, Rat, Cow, Goat WB, IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 67-175) antibodyCASP3 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 220-236), (C-Term) antibodyCASP3 Reactivity: Human WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 3 (CASP3) antibodyCASP3 Reactivity: Human, Mouse, Rat WB, IHC Host: Mouse Monoclonal 5E1 unconjugated
anti-Caspase 3 (CASP3) (pSer150) antibodyCASP3 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 3 (CASP3) (Internal Region) antibodyCASP3 Reactivity: Human, Mouse, Rat, Cow WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 3 (CASP3) (cleaved) antibodyCASP3 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C3 unconjugated
anti-Caspase 3 (CASP3) (AA 149-179), (Asp175) antibodyCASP3 Reactivity: Human, Rat WB, IHC (p), FACS Host: Rabbit Polyclonal RB25834 unconjugated
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- Application Notes
- Titration of the anti-Caspase-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the anti-Caspase-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- Caspase 3 (CASP3)
- Alternative Name
- Caspase-3 (CASP3 Products)
- Background
- CASP3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
- UniProt
- P42574
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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