ANGPTL3 antibody (AA 82-114)

Catalog No. ABIN3029953

Product Details anti-ANGPTL3 Antibody

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Binding Specificity: AA 82-114

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: A portion of amino acids 82-114 from the human protein was used as the immunogen for this ANGPTL3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ANGPTL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ANGPTL3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ANGPTL3

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Alternative Name: ANGPTL3 (ANGPTL3 Products)

Synonyms: fb60e11 antibody, fb66h02 antibody, wu:fb60e11 antibody, wu:fb66h02 antibody, zgc:111943 antibody, ANGPTL3 antibody, LOC100230785 antibody, ANG-5 antibody, ANGPT5 antibody, ANL3 antibody, FHBL2 antibody, hypl antibody, angiopoietin-like 3 antibody, angiopoietin like 3 antibody, angptl3 antibody, ANGPTL3 antibody, Angptl3 antibody

Background: ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.

UniProt: Q9Y5C1