AIM2 antibody (AA 1-50)
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- Target See all AIM2 Antibodies
- AIM2 (Absent in Melanoma 2 (AIM2))
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Binding Specificity
- AA 1-50
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AIM2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 1-50 from the human protein was used as the immunogen for this AIM2 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product AIM2 Primary Antibody
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anti-Absent in Melanoma 2 (AIM2) (AA 1-195) antibody
AIM2 Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 3C4G11 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 81-326) antibodyAIM2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (Internal Region) antibodyAIM2 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 4-32), (N-Term) antibodyAIM2 Reactivity: Human WB, FACS, IF Host: Rabbit Polyclonal RB23659 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-260) antibodyAIM2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 14-215) antibodyAIM2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 255-354) antibodyAIM2 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the AIM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the AIM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- AIM2 (Absent in Melanoma 2 (AIM2))
- Alternative Name
- AIM2 (AIM2 Products)
- Synonyms
- AIM2 antibody, PYHIN4 antibody, Gm1313 antibody, Ifi210 antibody, absent in melanoma 2 antibody, AIM2 antibody, Aim2 antibody
- Background
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. [UniProt]
- UniProt
- O14862
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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