PDGFRB antibody (AA 40-72)

Catalog No. ABIN3029811

Product Details anti-PDGFRB Antibody

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Binding Specificity: AA 40-72

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Purified

Immunogen: A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the PDGFR beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C for up to one month. For long term, aliquot the PDGFR beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Alternative Name: PDGFR beta (CD140b) (PDGFRB Products)

Synonyms: AI528809 antibody, CD140b antibody, PDGFR-1 antibody, Pdgfr antibody, CD140B antibody, IBGC4 antibody, JTK12 antibody, PDGFR antibody, PDGFR1 antibody, platelet derived growth factor receptor, beta polypeptide antibody, platelet derived growth factor receptor beta antibody, Pdgfrb antibody, PDGFRB antibody

Background: PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.

UniProt: P09619

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling