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TLR7 antibody

TLR7 Reactivity: Human, Mouse, Rat WB, FACS, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4952861
  • Target See all TLR7 Antibodies
    TLR7 (Toll-Like Receptor 7 (TLR7))
    Reactivity
    • 88
    • 41
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 86
    • 16
    Rabbit
    Clonality
    • 78
    • 24
    Polyclonal
    Conjugate
    • 51
    • 10
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This TLR7 antibody is un-conjugated
    Application
    • 59
    • 45
    • 23
    • 14
    • 14
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Antigen affinity
    Immunogen
    Amino acids QAHPYFWQCLKNALATDNHVAYSQVFKE of human TLR7 were used as the immunogen for the TLR7 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product TLR7 Primary Antibody
  • Application Notes
    Optimal dilution of the TLR7 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,Immunocytochemistry: 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the TLR7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    TLR7 (Toll-Like Receptor 7 (TLR7))
    Alternative Name
    TLR7 (TLR7 Products)
    Synonyms
    TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody
    Background
    TLR7 (Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.
    UniProt
    Q9NYK1
    Pathways
    TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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