Plakophilin 1 antibody (N-Term)

Catalog No. ABIN4949852

Product Details anti-Plakophilin 1 Antibody

Target: Plakophilin 1 (PKP1)

Binding Specificity: AA 1-27, N-Term

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Plakophilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Protein G affinity chromatography

Immunogen: A N-terminal human recombinant protein fragment was used as the immunogen for the Plakophilin 1 antibody. Its epitope maps to between amino acids 1-27 of human PKP1.

Clone: 10B2

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal dilution of the Plakophilin 1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Plakophilin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for Plakophilin 1

Target: Plakophilin 1 (PKP1)

Alternative Name: Plakophilin 1 (PKP1 Products)

Synonyms: PKP1 antibody, fb30d08 antibody, wu:fb30d08 antibody, AI528551 antibody, B6P antibody, plakophilin 1 antibody, plakophilin 1b antibody, PKP1 antibody, pkp1b antibody, Pkp1 antibody

Background: Recognizes a protein of 75  kDa, identified as Plakophilin 1 (PKP1). Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. PKP1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). PKP2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.