TLE4 antibody
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- Target See all TLE4 Antibodies
- TLE4 (Transducin-like Enhancer Protein 4 (TLE4))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TLE4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogen
- This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.
- Clone
- 4C4
- Isotype
- IgM
- Top Product
- Discover our top product TLE4 Primary Antibody
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- TLE4 (Transducin-like Enhancer Protein 4 (TLE4))
- Alternative Name
- TLE4 (TLE4 Products)
- Background
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Synonyms: ESG, BCE1, ESG4, GRG4, BCE-1, Grg-4, E(spI), Transducin-like enhancer protein 4, Groucho-related protein 4, TLE4, KIAA1261
Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
- Gene ID
- 7091
- UniProt
- Q04727
- Pathways
- WNT Signaling
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