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- Target See all RNF20 Antibodies
- RNF20 (Ring Finger Protein 20 (RNF20))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RNF20 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Purified by Protein G.
- Immunogen
- This RNF20 antibody is generated from a mouse immunized with a recombinant protein of human RNF20.
- Clone
- 4C6
- Isotype
- IgG1
- Top Product
- Discover our top product RNF20 Primary Antibody
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anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibody
RNF20 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (Internal Region) antibodyRNF20 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 576-625) antibodyRNF20 Reactivity: Human, Mouse, Dog, Cow, Guinea Pig, Pig, Hamster, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 108-157) antibodyRNF20 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig, Hamster, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibodyRNF20 Reactivity: Human IP Host: Rabbit Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1E4 unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-260) antibodyRNF20 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (N-Term) antibodyRNF20 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- RNF20 (Ring Finger Protein 20 (RNF20))
- Alternative Name
- RNF20 (RNF20 Products)
- Background
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Synonyms: BRE1, BRE1A, hBRE1, E3 ubiquitin-protein ligase BRE1A, BRE1-A, RING finger protein 20, RNF20
Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.
- Gene ID
- 56254
- UniProt
- Q5VTR2
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