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MBD3 antibody

MBD3 Reactivity: Human WB Host: Mouse Monoclonal 5C3 unconjugated
Catalog No. ABIN4911809
  • Target See all MBD3 Antibodies
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Reactivity
    • 69
    • 29
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 8
    • 2
    Mouse
    Clonality
    • 56
    • 13
    Monoclonal
    Conjugate
    • 41
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MBD3 antibody is un-conjugated
    Application
    • 45
    • 29
    • 9
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Purification
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    Purified His-tagged MBD3 protein was used to produced this monoclonal antibody.
    Clone
    5C3
    Isotype
    IgG1
    Top Product
    Discover our top product MBD3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Alternative Name
    MBD3 (MBD3 Products)
    Synonyms
    xmbd3 antibody, MGC69548 antibody, MBD3 antibody, DKFZp459N1635 antibody, AI181826 antibody, AU019209 antibody, methyl-CpG binding domain protein 3 S homeolog antibody, methyl-CpG binding domain protein 3 antibody, mbd3.S antibody, mbd3 antibody, MBD3 antibody, Mbd3 antibody
    Background

    Synonyms: Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3, MBD3

    Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.

    Gene ID
    53615
    UniProt
    O95983
    Pathways
    Chromatin Binding
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