MAP3K11 antibody
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- Target See all MAP3K11 Antibodies
- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MAP3K11 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogen
- This MAP3K11 monoclonal antibody is generated from mouse immunized with MAP3K11 recombinant protein.
- Clone
- 3T1
- Isotype
- IgM
- Top Product
- Discover our top product MAP3K11 Primary Antibody
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
- Alternative Name
- MAP3K11 (MAP3K11 Products)
- Synonyms
- MEKK11 antibody, MLK-3 antibody, MLK3 antibody, PTK1 antibody, SPRK antibody, 2610017K16Rik antibody, Mlk3 antibody, Mlk-3 antibody, RHOE antibody, mitogen-activated protein kinase kinase kinase 11 antibody, MAP3K11 antibody, Map3k11 antibody
- Background
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Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11
Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
- Gene ID
- 4296
- UniProt
- Q16584
- Pathways
- MAPK Signaling, Interferon-gamma Pathway
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